More than 70 years ago, Danny Thomas, then a struggling young entertainer with a baby on the way, visited a Detroit church. He was so moved during the Mass, he placed his last $7 in the collection box. With only a few coins left in his pocket, Danny prayed for a way to pay his looming hospital bills. The next day, he was offered a small part that would pay 10 times the amount he had given to the church. Danny had experienced the power of prayer.

Two years later, Danny had achieved moderate acting success in Detroit, but he was struggling to take his career to the next level. Once again, he turned to the church. Praying to St. Jude Thaddeus, the patron saint of hopeless causes, Danny asked the saint to "help me find my way in life, and I will build you a shrine."

His career took a turn for the better, and soon he moved his family to Chicago to pursue new opportunities. A few years later at another turning point in his life, Danny visited a church and remembered his pledge. Again he prayed to St. Jude and repeated his pledge to build a shrine to the saint if he would show him the way. In the years that followed, Danny's career flourished through films and television, and he became an internationally known entertainer. He remembered his pledge to build a shrine to St. Jude.

In the early 1950s, Danny began discussing with friends what concrete form his vow might take. Gradually, the idea of a children's hospital, possibly in Memphis, Tenn., took shape. In 1955, Danny and a group of Memphis business­men who had agreed to help support his dream seized on the idea of creating a unique research hospital devoted to curing cancer and other catastrophic diseases in children. More than just a treatment facility, this would be a research center for the children of the world.

Danny started raising money for his vision of St. Jude in the early 1950s. By 1955, the local business leaders who had joined his cause began area fundraising efforts to supplement Danny's benefit shows that brought scores of major entertainment stars to Memphis. Often accompanied by his wife, Rose Marie, Danny crisscrossed the United States by car, sharing his dream and raising funds at meetings and benefits. The pace was so hectic that Danny and his wife once visited 28 cities in 32 days. Although Danny and his friends, many of them from the Hollywood community, raised the money to build the hospital, they now faced the daunting task of funding its annual operation.

To solve this problem, Danny, of Lebanese descent, turned to fellow Americans of Arabic-speak­ing heritage. Believing deeply that these Americans should, as a group, thank the United States for the gifts of freedom given their parents, Danny also felt the support of St. Jude would be a noble way of honoring his immigrant ancestors who had come to America.

Danny's request struck a responsive chord. In 1957, 100 representatives of the Arab-American community met in Chicago to form ALSAC® with a sole purpose of raising funds to support St. Jude Children's Research Hospital®.

Since that time, with national headquarters in Memphis and regional offices throughout the United States, ALSAC has assumed full responsibility for all the hospital's fundraising efforts, raising hundreds of millions of dollars annually through benefits and solicitation drives among people of all ethnic, religious and racial backgrounds. More than 75 percent of St. Jude's operating budget is covered by public contributions generated by ALSAC fundraising programs. Today, ALSAC is the nation's largest health-care charity* and is supported by the efforts of more than 1 million volunteers nationwide.

Through striking improvements in the care of pediatric leukemias and numerous forms of solid tumors, St. Jude — which now has a daily operating cost of $2.4 million — has brought about improved health care for children all over the world. St. Jude's physicians and scientists have pioneered treatments that have helped push the overall survival rates for childhood cancers from less than 20 percent when the hospital opened in 1962 to more than 80 percent today.

From a promise of "Help me find my way in life, and I will build you a shrine" to the fulfillment of his dream, Danny lived to see his hospital become an international beacon of hope for the catastrophically ill children of the world. The founder of St. Jude and ALSAC died on Feb. 6, 1991, just two days after joining patients, parents and employees to celebrate the hospital's 29th anniversary. He was laid to rest in a family crypt at the Danny Thomas/ALSAC Pavilion on the grounds of the hospital. On July 12, 2000, his wife, Rose Marie, passed away and now lies with her beloved husband in the hospital's Memorial Garden. Today, their children, Marlo, Terre and Tony, carry on their parents' work and remain a driving force in fulfilling their father's mission. Danny Thomas is gone, but his dream lives on.

* Based on the 2015 Philanthropy 400 ranking by The Chronicle of Philanthropy